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生物通
5月
跨物种保守的 SIR2 抗噬菌体蛋白同源物通过 Toll 样受体通路介导人类 ...
为探究细菌与真核生物免疫蛋白的保守性,研究人员发现 SIRims 蛋白家族。人类成员 SIRal 通过 Toll 样受体(TLR)通路激活先天免疫,上调 ISGs 和促炎细胞因子,抑制 HSV-1 与细菌复制。该发现拓展了跨物种免疫保守研究,为免疫治疗提供新方向。 生物体普遍面临 ...
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