本研究揭示了RNA结合蛋白Rbm38在终末红细胞生成中的关键作用。研究人员通过构建基因敲除模型发现,Rbm38缺失导致小红细胞低色素性贫血、血红素合成障碍和游离原卟啉积累,证实其通过调控Fech基因的可变剪接、mRNA稳定性和翻译来维持铁代谢稳态,为红细胞 ...
本研究针对糖尿病引发的细胞血红素代谢紊乱问题,通过建立STZ诱导的I型糖尿病小鼠模型,探究铁螯合酶(FECH)在血红素合成通路中的调控机制。研究发现高血糖通过增强转录因子Sp1与FECH启动子的结合提升mRNA水平,但蛋白表达未同步增加,揭示FECH可能是血红素 ...
Lu X, Liu K, Zheng W, Zhang X, Shi J, Yu S, et al. Ferrochelatase Gene Variants Associated with Cholestasis in Adults: A Case Report. J Clin Transl Hepatol. 2025;13(2):173-177. doi: 10.14218/JCTH.2024 ...
Lauren Fech went on a 22-point tear for the Winona State University (WSU) women’s basketball team last Saturday, but it wasn’t enough to secure a victory over Minnesota State University Moorhead (MSUM ...
All the Latest Game Footage and Images from Fech the Ferret Fech The Ferret is a fast and loud parkour game about a (cute) pink ferret. Go run around, sometimes to the beat of electronic music. Make ...
Love your musical games and want to get into the rhythm? Fech The Ferret looks like a pretty clever blending of ideas. It's a fast-paced parkour platformer with seriously vibrant and inviting colours.
物种来源(人、小鼠、大鼠、豚鼠、兔、猕猴、山羊、绵羊、马、牛、猪、鸡、狗等其他物种多物种)相同的名称,不同的物种。 变性纯化后纯度还是挺不错的。 FECH蛋白;亚铁螯合酶(FECH)重组蛋白两个建议: 1、用非变性纯化样品去做EK酶切、纯化。 如果融合 ...
Just three months into the job, we catch up with Winchester Thurston’s new Head of School, Dr. Scott Fech. His distinguished career includes leadership positions at the University of Chicago’s ...
Mountainside Councilwoman Wendy Fech-Caccamo has withdrawn her bid for re-election. Glenn Mortimer, the Union County Republican Chairman and also a Mountainside Councilman, cited personal reasons for ...
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