在精神病遗传学研究领域,一个核心谜题数十年来悬而未决:尽管大量证据表明精神疾病具有很高的遗传性,但其背后的生物学机制却始终笼罩在“遗传力迷雾”之中。全基因组关联研究(GWAS)虽已成功识别出与精神分裂症、双相情感障碍、自闭症及抑郁症相关的数十个基因位点,然而,这些位点绝大多数位于非编码区域,而非基因内部。这些发现犹如在地图上标出了风险坐标,却未能揭示导致疾病的具体功能通路;遗传变异如何最终影响大脑 ...
First they sequenced it. Now they have surveyed its hinterlands. But no one knows how much more information the human genome holds, or when to stop looking for it. Ewan Birney would like to create a ...
Back in 2001, the Human Genome Project gave us a nigh-complete readout of our DNA. Somehow, those As, Gs, Cs, and Ts contained the full instructions for making one of us, but they were hardly a simple ...
ENCODE, the $185-million successor to the Human Genome Project, promises to reveal new details about our DNA. But controversy persists as geneticists remain at odds over one little f-word—"function" ...
In the 1970s, when biologists first glimpsed the landscape of human genes, they saw that the small pieces of DNA that coded for proteins (known as exons) seemed to float like bits of wood in a sea of ...
Sneha Revanur is a 19-year-old incoming junior at Stanford University, but she is already making waves in Washington as an activist on the ethical use of artificial intelligence (AI). Her organisation ...
Crypto-savvy developers are in short supply these days. Blockchain startups and protocols are fighting to onboard and train more engineers — an even tougher undertaking in a world where developing on ...
Posts from this topic will be added to your daily email digest and your homepage feed. The company cites speed of adoption and changes in the new smart home standard as reasons its Encode Plus smart ...
As first announced at WWDC 2021, iOS 15 evolves Apple Wallet to store keys for hotels, homes, and even cars. The Schlage Encode Plus is the first such consumer lock solution to take advantage of the ...
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